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Hair, Nails and Mucous Membranes |
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Selected Diseases of the Scalp
Nonscarring alopecias:
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Miniaturization
Androgenetic alopecia (AGA)
Female Hair Loss: Ludwig Classification
Female Androgenetic alopecia (AGA)
Ludwig Stage I
Ludwig Stage II
Ludwig Stage III
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- 50% of men and women experience androgenetic alopecia by age 50
Each individual follicle is genetically marked to become bald or
not to become bald
Uptake, metabolism and 5-alpha reduction of testosterone to
dihydrotesterone is increased in balding areas
Hair miniaturizes with each cycle
Treatment: oral finasteride, topical minoxidil solution, or hair
transplant surgery
Norwood-Hamilton Classification
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Frontal-temporal recession
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Vertex Thinning
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Early Norwood-Hamilton
Stage IV
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Late Norwood-Hamilton
Stage IV
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Norwood-Hamilton
Stage V
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Norwood-Hamilton
Stage VI
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Norwood-Hamilton
Stage VII
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Alopecia areata (AA)
AA
AA
AA
AA and Vitiligo
AA
Pathogenesis of AA
Histopathology of AA
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- Alopecia areata
- Circumscribed oval circinate patch or patches; periphery may show short broken hairs
- Exclamation point hairs which taper proximally can be seen
and are pathognomonic
- Asymptomatic, but there may be paraesthesias or tenderness
- May affect eyebrows, eyelashes and beard
- Course is unpredictable. However, early age of onset and
atopy may indicate a lengthy course with increased incidence of alopecia totalis.
- 83% of all cases resolve in 3 years without treatment
- 25% give a family history. There are 2 sets of identical
siblings that have had it simultaneously.
- Associations: 8% thyroid disease, 4% vitiligo
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Alopecia areata
circumscripta |
Alopecia areata
circumscripta |
Circumscript Alopecia areata (AA) |
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Alopecia universalis |
Alopecia universalis |
Alopecia universalis |
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Alopecia totalis |
White Hairs |
Ophiasis |
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