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Here are 19 different
images of malignant melanoma, with specific features of change identified
in each:
Click on the thumbnail photo for a larger image.
1. This lesion demonstrates significant variation in pigmentation,
ranging from black to red. There is an eccentric area of outgrowth
of pigment. There is also scale on the surface, and loss of symmetry.
2. This lesion shows marked asymmetry, variation in pigmentation,
and irregular outlines. There is a white area on the upper part where
the lesion has regressed.
3. This slowly-growing lesion has been present on the medial upper
calf for one year, and has increased in size. It demonstrates variation
in pigmentation, poorly outlined margins, and varigate eccentric pigment.
4. This poorly-demarcated asymmetrical lesion has variation in color
from pink to brown and black. Grey areas are noted on the lower right,
where the lesion has been partially reabsorbed by the body, a process
known as regression.
5. This is a variegated lesion, which has grown in opposite directions.
The central part has regressed, causing the pale area, and the pigment
is irregular.
6. This is a Lentigo maligna, a slow-growing melanoma limited to the
upper layer of the skin. It shows irregular pigmentation. The pink
area at the left side of the lesion in a biopsy site.
7. This irregular pigmented lesion has loss of symmetry and irregular
pigmentation.
8. This lesion, which has been growing on the medial upper thigh,
shows a nodule, irregular pigmentation. One area on the right side
shows loss of pigmentation, characteristic of an amelanotic melanoma.
9. This lesion of the mid upper back shows loss of central pigment,
an irregular outline, and poor symmetry. There is some scale on the
surface.
10. This lesion is on the upper thigh has been slowly growing over
several years. It is highly asymmetrical, with significant variation
in pigmentation.
11. This patient had a mole on the chest for more than 20 years. It
began to change rapidly with the appearance of the black lump. The
black bumps beyond the edge of the mole are from spread of the melanoma
through the skin.
12. This lesion on the outer part of the foot shows the very poorly-demarcated
features of a malignant melanoma, areas of regression and irregular
pigmentation.
13. This is a melanoma arising in a mole on the upper chest of a patient
with multiple moles. The pigmentation is irregular and varied, the
margins irregular, and it has been growing.
14. This flat lesion has evolved over one year with an increase in
size, irregular pigment, and loss of marginal definition. These are
the hallmarks of a Lentigo maligna which has the potential to become
an invasive melanoma.
15. One year old mole on the outer thigh of a young woman was noted
by a friend at a party. It has an irregular shape and varied pigmentation.
16. This mole has a one year history of growing, with the appearance
of asymmetry, an irregular outline, and varied pigment.
17. This mole has been present on this gentleman's forearm for over
40 years. In the last 6 months it has grown rapidly, become elevated,
and changed color.
18. This itchy mole has been present on the upper back of a young
man for two years. It has undergone recent growth, and developed areas
of pink, gray, and dark brown.
19. This melanoma has grown over three years. It demonstrates every
feature of ABCD. It is asymmetric with a collage of scalloped edges
from localized growth. The borders are irregular and poorly defined.
The colors range from black to brown to pink to white. The diameter
has increased over time.
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